Archives
- 2018-07
- 2018-10
- 2018-11
- 2019-04
- 2019-05
- 2019-06
- 2019-07
- 2019-08
- 2019-09
- 2019-10
- 2019-11
- 2019-12
- 2020-01
- 2020-02
- 2020-03
- 2020-04
- 2020-05
- 2020-06
- 2020-07
- 2020-08
- 2020-09
- 2020-10
- 2020-11
- 2020-12
- 2021-01
- 2021-02
- 2021-03
- 2021-04
- 2021-05
- 2021-06
- 2021-07
- 2021-08
- 2021-09
- 2021-10
- 2021-11
- 2021-12
- 2022-01
- 2022-02
- 2022-03
- 2022-04
- 2022-05
- 2022-06
- 2022-07
- 2022-08
- 2022-09
- 2022-10
- 2022-11
- 2022-12
- 2023-01
- 2023-02
- 2023-03
- 2023-04
- 2023-05
- 2023-06
- 2023-07
- 2023-08
- 2023-09
- 2023-10
- 2023-11
- 2023-12
- 2024-01
- 2024-02
- 2024-03
- 2024-04
- 2024-05
-
Gu et al had previously reported that a soluble peptide
2018-11-09
Gu et al. had previously reported that a soluble peptide, R9-caPep, derived from the interdomain loop of the replication clamp PCNA (proliferating cell nuclear antigen) selectively inhibited the proliferation of neuroblastoma Cyanine5.5 alkyne Supplier that harbored MYCN amplifications (Gu et al.,
-
Our analysis revealed that ZIKV
2018-11-09
Our analysis revealed that ZIKV strongly impairs cell cycle progression of RGP cells, consistent with recent reports (Qian et al., 2016; Li et al., 2016). Surprisingly, WNV-infected RGP cells did not show such cell cycle abnormalities. Our comparative analysis should therefore prove very powerful to
-
Dysfunction of the circadian clocks plays
2018-11-09
Dysfunction of the circadian clocks plays a role in mood disorders (). It is not known, however, whether they have a causal role in the etiology or display their effects on mood later during the pathogenesis. Basic research findings from mice recently pointed out that circadian rhythm abnormalities
-
Although more GWAS on sepsis
2018-11-09
Although more GWAS on sepsis traits will be accomplished in the coming years, it is worth noting that these studies allow analyzing a modest fraction of all existing variants in our genome. In , present their results from a study using a promising alternative taking advantage of high-throughput DNA
-
The succesful development of flavivirus vaccines began years
2018-11-09
The succesful development of flavivirus vaccines began 80years ago in 1937 with the yellow fever YFV17D live-attenuated vaccine (Monath, 2008). Since then, >600 million people have been vaccinated, with 98% protection and a >10year persistence of vaccine–induced immunity (Barrett and Teuwen, 2009).
-
br Materials and Methods br Results br Discussion The
2018-11-09
Materials and Methods Results Discussion The crystal structure of ClfA N2N3 in complex with the Fab fragment generated from tefibazumab defines the epitope for this inhibiting mAb, which to our surprise is located on top of the N3 subdomain. Through biochemical studies we demonstrate that t
-
The anatomical differences found between the Chinese and U
2018-11-09
The anatomical differences found between the Chinese and U.S. child templates parallel the findings of imidazoline receptors differences between these two developmental populations from previous research. For example, Guo et al. (2007) found different trajectory of GM development between Chinese an
-
br La Comunidad Econ mica Europea Antes de
2018-11-09
La Comunidad Económica Europea Antes de que se concretara un auténtico proyecto y que se volviera un objetivo preciso de la política gubernamental de los países europeos, la idea europea se limitaba ci-1033 los escritos de filósofos y escritores. La perspectiva de los Estados Unidos de Europa, se
-
br V Alternativa Bolivariana para Am rica Latina
2018-11-09
V. Alternativa Bolivariana para América Latina y el Caribe-Tratado de Comercio de los Pueblos Como bien lo sintetiza Naviero, O de L. (2013, P 293): “Tanto el Plan como la Constitución definen una organización económica dual. Por un lado, se definen los recursos estratégicos, destinados a la expo
-
Loyo suggests that the construction of a
2018-11-09
Loyo (2006) suggests that the construction of a yield curve in the Brazilian financial system could become viable if the National Treasury issued long-term floating rate bonds, with higher returns, and in the meantime the Central Bank decreased the Selic rate, bringing more volatility to this rate.
-
A 779 Strengths of this analysis include that the biomarker
2018-11-09
Strengths of this analysis include that the biomarker assay was analytically validated, the data were from a randomized clinical trial, and the hypothesis was prospectively stated prior to data unblinding (Khleif et al., 2010). The fact that a single biomarker was identified minimized the potential
-
The essential autophagy gene beclin BECN is a haploinsuffici
2018-11-09
The essential autophagy gene beclin 1 (BECN1) is a haploinsufficient tumor suppressor (Liang et al., 1999; Qu et al., 2003; Yue et al., 2003) that is also located on the breast cancer tumor susceptibility chromosomal locus 17q21, ~150kb centromeric to BRCA1 (Aita et al., 1999). Monoallelic loss of B
-
We identified two critical events that
2018-11-09
We identified two critical events that might be associated with pathomechanism collagen VI deficiency in our mice. The first event is a non-cell-autonomous effect from the collagen VI deficiency, causing the dysregulation in the number of myofibers in a muscle. In normal control mice, myofibers incr
-
Chimera have been generated in
2018-11-08
Chimera have been generated in the lab exclusively as interspecific chimera between mouse species (Rossant and Frels, 1980) and recently rats (review by Iannaccone and Jacob, 2009). Even within the rodent family, intergeneric chimera between mice and voles did not succeed (Mystkowska, 1975a, 1975b).
-
br Results br Discussion As the first step
2018-11-08
Results Discussion As the first step of our method, hiPS cells underwent differentiation into definitive endoderm by treatment with activin A and the GSK3β inhibitor CHIR99021. In other methods, activin A and Wnt 3a have mainly been used to induce definitive endoderm (D\'Amour et al., 2006; Kr
14056 records 919/938 page Previous Next First page 上5页 916917918919920 下5页 Last page