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br Acknowledgments We thank all the
2019-04-30
Acknowledgments We thank all the ultramarathon runners who participated in this study and all the doctors, nurses, and emergency medical technicians who provided professional care at the ultramarathon race. We also thank our colleagues at Soochow University, Taipei, Taiwan and the Chinese Taipei
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The functional analysis of this V
2019-04-30
The functional analysis of this V1764fsX1786 mutation is shown in Fig. 3B; no current was observed, indicating severe loss-of-function. Although we did not investigate the mechanisms of this complete reduction in Na+ current in this mutation, Herfst et al [19]. reported a similar frameshift mutation
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Certainly dynamic interactions between DTCs and stromal cell
2019-04-30
Certainly, dynamic interactions between DTCs and stromal I-BET-762 within the bone microenvironment disrupt bone homeostasis, which is normally tightly controlled, to fuel metastatic progression [18] (Table 1). For example, it is well established that osteolytic breast cancer DTC-derived factors, s
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Resulta dif cil un censo de poetas aunque
2019-04-30
Resulta difícil un censo de poetas (aunque la Coordinación Nacional de Literatura del inba o de Conaculta probablemente cuente con las herramientas para hacerlo) y volver PF-3758309 trillar sobre un concepto ingenioso como el de asamblea de poetas pergeñado por Zaid en 1980 parece imposible ante el
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br A gest o hospitalar nas unidades mantidas Talvez seja
2019-04-30
A gestão hospitalar nas unidades mantidas Talvez seja o produto de mais expressividade que as oss divulgam. A forma como se gerencia o hospital é ctap garantia de colheita dos resultados, seu game over junto à sociedade e junto a sua contratante, a Secretaria de Saúde. É a procura por legitimar a
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La descripci n que se hace del
2019-04-30
La descripción que se hace del accidente es distintiva de la forma en que los personajes de Ramos entran en contacto con los objetos, incapaces de percibir –y, por tanto, de razonar y discriminar- lo que los rodea se ven obligados GDC-0994 vivir en la angustia de irlo conociendo lenta y fragmentaria
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El problema del populismo ocup de manera temprana la obra
2019-04-30
El problema del populismo ocupó de manera temprana la obra de Ernesto Laclau. Su primera obra, publicada en 1977 como Politics and ideology in marxist theory. Capitalism, fascism, populism, incluye el capítulo “Hacia una teoría del populismo”. La preocupación por el asunto no es meramente teórica si
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br Algunas conclusiones y una agenda abierta El
2019-04-29
Algunas conclusiones y una agenda abierta El populismo, como un modo de inclusión radical que pone en cuestión los límites de la comunidad, ha sido una clave interpretativa recurrente pppa la vez que obliga a poner atención en el contenido de las articulaciones. Esto tiene dos efectos, por un lad
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br Conflict of interests br Introduction Recently Zhou et
2019-04-29
Conflict of interests Introduction Recently Zhou et al. developed the new National Comprehensive Cancer Network (NCCN)- International Prognostic Index (IPI) to predict survival in the rituximab era more accurately than the older IPI system [1]. Although reports that used the same prognostic st
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After the success of the Millennium Development
2019-04-29
After the success of the Millennium Development Goals and the reduction in more than 50% of child mortality in children younger than 5 years (Countdown to 2015 report), the survive and thrive motto was given prominence by the Sustainable Development Goals (SDGs). For all children to thrive, we need
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In Taiwan newborn screening for GA I started in and
2019-04-29
In Taiwan, newborn screening for GA-I started in 2001 and has been mandated since 2006; however there have been only a few small-scale reports describing GA-1 in Taiwan. We describe our experience with Taiwan\'s largest newborn screening population. This included eleven patients diagnosed with GA-1
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br Conclusion br Conflict of interest br Introduction
2019-04-29
Conclusion Conflict of interest Introduction In recent years, the development of transvenous electrodes and downsized generators has permitted electrophysiologists to implant cardiac implantable electrical devices (CIEDs), including high voltage devices such as implantable cardioverter-defi
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If the QT interval is markedly prolonged the
2019-04-29
If the QT interval is markedly prolonged, the polymorphic VT is most likely Torsades de points (TdP, a specific form of polymorphic VT in which the QRS complexes seem to twist around the isoelectric line), which is attributable to congenital or acquired LQTS. Congenital LQTS is an ion channel disord
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The tumor microenvironment is enriched with EMVs
2019-04-29
The tumor microenvironment is enriched with EMVs that are derived not only by proliferating tumor cells, but also from infiltrating macrophages and neutrophils, and support tumor cell survival, growth, invasion and metastasis. Tumor derived EMVs also have the potential to modulate surrounding stroma
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br Advanced genetic and genomic
2019-04-29
Advanced genetic and genomic technologies Many of the causative genes described here were identified using a candidate gene approach, in which genes are selected based on findings of preceding genetic linkage analysis or molecular pathway information [63]. Considering that the human genome encod
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