• Introduction Cyclin dependent kinases CDKs are

  2021-01-23

  

  Introduction Cyclin dependent kinases (CDKs) are a family of proline-directed serine/threonine kinases with roles in regulation of crucial cellular processes such as blz and transcription [1]. One of the unifying features of this family is its dependence on association with cyclins/cyclin-like regu

• br Conflict of interest br Acknowledgments Dr Hauger

  2021-01-23

  

  Conflict of interest Acknowledgments Dr. Hauger was supported by a BLR&D Merit Review grant from the Department of Veterans Affairs, Veterans Health Administration, Office of Research and Development. Dr. Hauger also received support from the VA Center of Excellence for Stress and Mental Healt

• In this study we observed alterations in

  2021-01-23

  

  In this study, we observed alterations in mRNA levels of CRF receptors in the PFCx and Hip during the development of sensitization. In particular, in the Hip both CRF receptors showed significantly increased DNQX disodium salt mg when the sensitization condition was established. Similarly, CRF2 rec

• On the other hand the

  2021-01-23

  

  On the other hand, the properties of collagen materials could be efficiently improved by proper chemical modification. The crosslinking agents for collagen generally involve aldehydes (e.g., glutaraldehyde (GA), isocyanates (e.g., hexamethylene diisocyanate (HMDI), photoreactive agents, polyepoxy c

• Cy5 EGFP mRNA Located on the fore tarsals

  2021-01-23

  

  Located on the fore-tarsals of the front pair of legs, the Haller’s organ is presumed central to tick chemosensation. Recent genomic, transcriptomic and proteomic investigations have identified several families of transmembrane proteins in the forelegs of ticks that are likely involved in olfactory

• Where does this transfer process occur The

  2021-01-23

  

  Where does this transfer process occur? The maternal side of the placenta is textured and spongy looking. The surface has 20–30 distinctive compartments named cotyledons, inside of which are the chorionic villi that form the principal functional structural unit of the placenta. These villi are compl

• The indigenous populations living at high mountain regions o

  2021-01-23

  

  The indigenous populations living at high mountain regions of the Himalayas represent successful human myosin to hypoxia. These populations have undergone selective positive natural selection over millennia across several genomic loci and exhibit unique respiratory, cardiopulmonary and haematologica

• Methacholine MCh is a bronchoconstrictive agent that has bee

  2021-01-23

  

  Methacholine (MCh) is a bronchoconstrictive agent that has been widely used in the diagnoses of airway narrowing and hyperresponsiveness (Jonasson et al., 2009). MCh induces muscle contractions by stimulating the muscarinic cholinergic receptors that are found in both the airways and the lung parenc

• br Discussion Nowadays data of uncommon EGFR

  2021-01-23

  

  Discussion Nowadays, data of uncommon EGFR mutations are limited, considering that patients carrying these rare alterations are usually excluded from clinical trials. Available survival data of activity of EGFR TKIs on this class of mutations, coming from a small number of usually retrospective s

• In addition to G coupling it is important to consider

  2021-01-23

  

  In addition to Gα coupling, it is important to consider that the transition from goal-directed to habitual drug taking also relies on striatal D2R-A2AR heterodimers. Following cocaine self-administration, D2R-A2AR density is increased in the NAc, leading to greater antagonism of the inhibitory (anti

• As part of a program

  2021-01-22

  

  As part of a program to explore the key binding interactions between the core of 1 and DGAT-1 a systematic analysis of the aminopyrimidine subunit was initiated. A potential approach to improving passive permeability within this series would be to increase lipophilicity via incorporation of substitu

• Introduction Collagen deposition is a common feature found i

  2021-01-22

  

  Introduction Collagen deposition is a common feature found in cancerous tissues and fibrotic organs/lesions. It is now well accepted that collagen deposition is not just a consequence of disease, but that it can also trigger a vicious cycle. Both chemical and physical signals elicited from collagen

• A small subset of compounds composed the triazino indole clu

  2021-01-22

  

  A small subset of compounds composed the 5-[1,2,4]triazino[5,6-]indole cluster (). This series of compounds was characterised by a central heterocyclic core with an R1 alkyl amine chain, required for potency (. , , and ), with preference for morpholine over piperidine (. ). The scaffold can be subst

• br Prostaglandin D PGD is derived from the metabolism of

  2021-01-22

  

  Prostaglandin D (PGD) is derived from the metabolism of arachidonic pd0325901 australia by cyclooxygenases and downstream PGD synthases. In the immune system, PGD is mainly produced by mast cells but also although at lower levels, by macrophages and Th2 lymphocytes. PGD binds to three different r

• br The amygdala complex The amygdala

  2021-01-22

  

  The amygdala complex The amygdala complex is composed of distinct nuclei and subdivisions including the lateral (LA), basolateral (BL), and basomedial (BM) amygdala; the medial (Imp), lateral paracapsular (lpc), and main intercalated cell cluster (IN); and the lateral and medialcentral amygdala (

16423 records 745/1095 page Previous Next First page 上5页 741742743744745 下5页 Last page