• La muerte violenta tiene un impacto diferencial por g

  2018-10-25

  

  La muerte violenta tiene un impacto diferencial por género. Años atrás, el feminicidio convocó al análisis académico de las estructuras de la violencia en esta localidad. Rosa-Linda Fregoso habló de un orden necropolítico que impera en el estado de Chihuahua. En este orden, había ya una concordancia

• Por ello la igualdad de

  2018-10-25

  

  Por ello, la igualdad de género y los derechos de las mujeres constituyen una agenda global, un desafío para cada país y para la sociedad mundial en su conjunto (). La decisión de establecer Mujeres en el año 2010 refleja la inquietud por la lentitud del cambio en el mundo y en cada país. Mujeres

• Adicionalmente el secretario de turismo de la regi

  2018-10-25

  

  Adicionalmente, el secretario de turismo de la región señaló que otorgar permiso para una reunión pública les daría a homosexuales legitimidad para ir en contra de “las buenas costumbres” (valores familiares) y las normas morales de la sociedad mexicana (Opuestos los alcaldes a la Reunión de Homosex

• br Materials and methods br Verification and authentication

  2018-10-24

  

  Materials and methods Verification and authentication Karyotyping was performed at the Center for Applied Human Molecular Genetics, Kennedy Center, Glostrup, Denmark. At least 10 metaphases were analysed per sample with an approximate resolution of 550 to 600 bands per haploid genome. The resu

• br Mat http www apexbt com media diy images

  2018-10-24

  

  Material andmethods Results anddiscussion Conclusions Here we report a comprehensive and unique transcriptomic study of the kinetics of gene SM-164 during ASC adipogenesis in vitro. Despite the limitation of the study design including the use of relatively late passage ASCs and the lack of

• Human ESC culture and processing were performed

  2018-10-24

  

  Human ESC culture and processing were performed in a grade A tissue culture cabinet in a grade B clean room environment monitored for particulate and microbiological contamination during cell processing in accordance with Rules and Guidance for Pharmaceutical Manufacturers and Distributors — The Ora

• br Resource table br Resource details Multiple endocrine

  2018-10-24

  

  Resource table Resource details Multiple endocrine neoplasia type 1 (MEN1) (also termed Wermer syndrome) is an autosomal dominant hereditary which is caused by mutations on the tumor suppressor gene MEN1. MEN1 is characterized by tumorigenesis mainly in endocrine organs including parathyroid g

• With these results we provide evidence that

  2018-10-24

  

  With these results, we provide evidence that the transplantation of iPSC-derived NSCs could have a beneficial role in modifying the course of SMARD1. Regarding the translational safety of iPSC-derived cells, one major finding of this study is that adverse events such as tumorigenesis or abnormal gro

• Increased DA secretion from SZ hiPSC neurons is consistent w

  2018-10-24

  

  Increased DA secretion from SZ hiPSC neurons is consistent with the ability of current antipsychotics, functioning as D2 DA receptor antagonists, to ameliorate the positive symptoms of SZ (Seeman, 1987; Coyle and Konopask, 2012; Eyles et al., 2012). Interestingly, because current antipsychotics lack

• Potential sources of NSCs include cell lines pluripotent

  2018-10-24

  

  Potential sources of NSCs include cell lines, pluripotent stem cell-derived NSCs, and primary NSCs harvested from fetal or adult animals. Some immortalized NSC lines can engraft and migrate extensively (Snyder et al., 1995), but they may have unstable genomes or pose a risk of tumorigenesis (Koso et

• Mechanisms underlying CIPN include direct and indirect

  2018-10-24

  

  Mechanisms underlying CIPN include direct and indirect effects on sensory nerves such as damage to neuronal cell bodies in the dorsal root ganglion, alteration of the amplitude of the sglt or conduction velocity (Argyriou et al., 2012; Sisignano et al., 2014). Whereas CIPN may be reversible for som

• Overall our robust transcriptome data in cells undergoing hi

  2018-10-24

  

  Overall, our robust transcriptome data in pdgfr undergoing hiPSC reprogramming showed dramatic changes in cell signaling pathways, human-specific AS, and ASE during the progressive cell fate change of fibroblasts to iPSCs (Figure 6E). The data will broaden the knowledge of the reprogramming process

• Importantly STS and STS have been shown to have overlapping

  2018-10-24

  

  Importantly, STS1 and STS2 have been shown to have overlapping functions (Carpino et al., 2002; Carpino et al., 2004). However, although expansion of LSK, increased serial colony growth, and hyperphosphorylation of FLT3 were largely attributable to the loss of STS1, further loss of STS2 strengthened

• br Experimental Procedures br Author Contributions

  2018-10-24

  

  Experimental Procedures Author Contributions Acknowledgments We thank Y. Sasai (RIKEN, Japan) for the RAX-GFP mESC line, M. Wegner (University of Erlangen, Germany) for SOX9, E. Tanaka (CRTD, Germany) for RAX and CRX, and D. Forrest (NIDDK, USA) for TRβ2 antibodies. We thank J. Brzezinski (

• qRT PCR showed that the expression of the PRC core

  2018-10-24

  

  qRT-PCR showed that the expression of the PRC2 core components Ezh2, Suz12, and Eed was not reduced upon Dicer deletion (Figure 2A). Similarly immunoblotting showed no reduction of EZH2, SUZ12, or JARID2 proteins or global H3K4me3 or H3K27me3 (Figure 2B). Cellular fractionation experiments confirmed

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