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phenylephrine hydrochloride br Ethics approval br Acknowledg
2018-11-09
Ethics approval Acknowledgments Introduction Low socioeconomic status (SES) is frequently found to be associated with poor health outcomes, despite substantial advances in prevention and treatment of disease (Phelan & Link, 2005; Braveman, Cubbin, Marchi, Egerter, & Chavez, 2001; Janssen, B
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The hippocampus is a region with
2018-11-09
The hippocampus is a region with diverse functions, including the ability to remember specific information about events, such as where and when events occurred. These functions appear to develop around two years old in children, but show great improvement over the next four years (Gomez and Edgin, 2
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Cross talk between the various
2018-11-09
Cross talk between the various systems is apparent with several well-described interactions such as that between C4-binding protein (C4BP) that regulates complement by inhibiting the classical initiation pathway and protein S, the latter being a cofactor for activated protein C, a regulator of coagu
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MTT In addition there is abundant evidence
2018-11-09
In addition, there is abundant evidence of altered Ca2+ dynamics in MTT with increased age (Toescu et al., 2004) and oxidative stress (Camandola and Mattson, 2011), which are partially mediated by transient receptor potential (TRP) channel dysfunction (Pena and Ordaz, 2008). Notably, TRP melastati
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br Materials and Methods br Results br
2018-11-09
Materials and Methods Results Discussion The homolog of the human tumor suppressor SCRIB was first characterized in Drosophila (Bilder et al., 2000). The product of human SCRIB, Scribble, is a multidomain protein acting as scaffold involved in multiple signaling pathways. Scribble is deregu
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br Conclusion The following are the supplementary data relat
2018-11-09
Conclusion The following are the supplementary data related to this article. Authors Contributions Declaration of Competing Interests Funding This work was conducted on behalf of the Early Cancer Detection Consortium, within the programme of work for work packages 1 & 2. The Early Cance
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Gu et al had previously reported that a soluble peptide
2018-11-09
Gu et al. had previously reported that a soluble peptide, R9-caPep, derived from the interdomain loop of the replication clamp PCNA (proliferating cell nuclear antigen) selectively inhibited the proliferation of neuroblastoma Cyanine5.5 alkyne Supplier that harbored MYCN amplifications (Gu et al.,
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Our analysis revealed that ZIKV
2018-11-09
Our analysis revealed that ZIKV strongly impairs cell cycle progression of RGP cells, consistent with recent reports (Qian et al., 2016; Li et al., 2016). Surprisingly, WNV-infected RGP cells did not show such cell cycle abnormalities. Our comparative analysis should therefore prove very powerful to
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Dysfunction of the circadian clocks plays
2018-11-09
Dysfunction of the circadian clocks plays a role in mood disorders (). It is not known, however, whether they have a causal role in the etiology or display their effects on mood later during the pathogenesis. Basic research findings from mice recently pointed out that circadian rhythm abnormalities
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Although more GWAS on sepsis
2018-11-09
Although more GWAS on sepsis traits will be accomplished in the coming years, it is worth noting that these studies allow analyzing a modest fraction of all existing variants in our genome. In , present their results from a study using a promising alternative taking advantage of high-throughput DNA
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The succesful development of flavivirus vaccines began years
2018-11-09
The succesful development of flavivirus vaccines began 80years ago in 1937 with the yellow fever YFV17D live-attenuated vaccine (Monath, 2008). Since then, >600 million people have been vaccinated, with 98% protection and a >10year persistence of vaccine–induced immunity (Barrett and Teuwen, 2009).
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br Materials and Methods br Results br Discussion The
2018-11-09
Materials and Methods Results Discussion The crystal structure of ClfA N2N3 in complex with the Fab fragment generated from tefibazumab defines the epitope for this inhibiting mAb, which to our surprise is located on top of the N3 subdomain. Through biochemical studies we demonstrate that t
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The anatomical differences found between the Chinese and U
2018-11-09
The anatomical differences found between the Chinese and U.S. child templates parallel the findings of imidazoline receptors differences between these two developmental populations from previous research. For example, Guo et al. (2007) found different trajectory of GM development between Chinese an
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br La Comunidad Econ mica Europea Antes de
2018-11-09
La Comunidad Económica Europea Antes de que se concretara un auténtico proyecto y que se volviera un objetivo preciso de la política gubernamental de los países europeos, la idea europea se limitaba ci-1033 los escritos de filósofos y escritores. La perspectiva de los Estados Unidos de Europa, se
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br V Alternativa Bolivariana para Am rica Latina
2018-11-09
V. Alternativa Bolivariana para América Latina y el Caribe-Tratado de Comercio de los Pueblos Como bien lo sintetiza Naviero, O de L. (2013, P 293): “Tanto el Plan como la Constitución definen una organización económica dual. Por un lado, se definen los recursos estratégicos, destinados a la expo
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