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To overcome these resistance mechanisms in APL cells
2019-05-27
To overcome these resistance mechanisms in APL cells, a number of drugs have been tested. Tamibarotene is approximately 10 times more potent than ATRA as an in vitro inducer of differentiation, and is chemically more stable than ATRA [5]. Although the precise mechanism of the combination of tamibaro
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ZIKV is a flavivirus related to dengue virus DENV and
2019-05-27
ZIKV is a flavivirus related to dengue virus (DENV) and historically has been transmitted by the same mosquito species, (). There is no available treatment or vaccine so disease control is limited to the management of mosquitoes which currently relies on either insecticides or the destruction of la
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br Discussion IUI with controlled ovarian hyperstimulation h
2019-05-27
Discussion IUI with controlled ovarian hyperstimulation has been used over the years as a treatment for mild male factor, anovulation, and unexplained infertility. It is less expensive and less invasive than other assisted reproductive techniques. Therefore, these advantages have made the techniq
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Although the CHADS score is useful for evaluating
2019-05-27
Although the CHADS2 score is useful for evaluating the risk of stroke in NVAF patients, about half of all NVAF patients have a score of or 1 [7]. There are no clear guidelines on whether warfarin should be administered or not, to these patients because the risk of annual incidence of stroke is so lo
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All patients with symptomatic cardiac AL amyloidosis
2019-05-27
All 4 patients with symptomatic cardiac AL amyloidosis had poor prognoses. The median survival period for these 4 patients was 12.3 months (minimum=4 months, maximum=28 months) (Table 1). The patient in Case 2, whose BNP level was the highest of the 4 patients, had the shortest survival period. Howe
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The study by Wan Ling Wong and colleagues
2019-05-24
The study by Wan Ling Wong and colleagues examines the overall prevalence of age-related macular degeneration. In agreement with previous studies, Wong and colleagues have projected that 196 million people will be affected by age-related macular degeneration in 2020, increasing to 288 million by 204
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br In a reanalysis of our results
2019-05-24
In a reanalysis of our results, Michelle Remme and colleagues (October, 2015) found that “secondary schooling might [even] be as good an HIV investment as male circumcision”, not to mention more expensive biomedical options. As Remme and colleagues rightly point out, we had excluded from our cost-
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Interpretation AMWHO is a useful forum for students to impro
2019-05-24
Interpretation AMWHO is a useful forum for students to improve their knowledge of global health issues, and sharpen their skills in diplomacy, communication, problem solving, and conflict resolution. Emory University (Atlanta, GA, USA) will host the next national AMWHO conference in October, 2016. E
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The distribution of the types of cancer is also interesting
2019-05-24
The distribution of the types of cancer is also interesting. Theoretically, the type of cancer should not have impact on a patient\'s place of death, and the rate should be approximately the same in both groups. However, a previous population-based study in Taiwan reported that respiratory tract can
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atp citrate lyase inhibitor Conversion of cholesterol to bil
2019-05-24
Conversion of cholesterol to bile acids is the only significant catabolic pathway for elimination of excessive cholesterol in our body. Bile acids have long been recognized as important physiological agents that facilitate atp citrate lyase inhibitor of dietary fats, steroids, drugs, and lipid solu
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To better understand how the unpaid status
2019-05-24
To better understand how the unpaid status of internships at WHO headquarters might affect their international accessibility, together with past and present intern colleagues, we did an online survey during two summer intern cohorts (2011 and 2013). The survey, which was distributed via email to all
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In Blake Alkire and colleagues now
2019-05-24
In , Blake Alkire and colleagues now provide additional measures to help us gain political priority on the public health agendas. In this study, Alkire and colleagues modelled access to surgery in 180 countries on the basis of four criteria: timeliness, surgical capacity, safety, and affordability.
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Esta idea se reforz con uno de
2019-05-24
Esta idea se reforzó con uno de los elementos identitarios oficiales de la organización, su propio escudo. La comil tomó cuatro de las características reconocibles del pgt histórico; es decir, las siglas, la estrella, la hoz y el martillo, y el círculo que enmarcó todos estos símbolos, mismos que d
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In this study we analyzed the biological effects of two
2019-05-24
In this study, we analyzed the biological effects of two novel GATA2 mutations, which were identified in adult de novo AML patients. Materials and methods The diagnosis of AML was based on the morphology, histopathology, the expression of leukocyte differentiation RGDfK and/or the French–Americ
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Countdown to concluded its tasks
2019-05-23
Countdown to 2015 concluded its tasks after the launch of its seventh global report at the Maternal Newborn Health conference in Mexico City, October, 2015. It is now relaunched as Countdown to 2030 (CD2030), retaining and enhancing the successful multi-institutional network with over a decade of he
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